In a new series for ITV, eight celebrities will spend three weeks on a strict diet and exercise regime to see if they can turn back the clock.
Sardinia has been named one of the world's Blue Zone areas, which are places where people live longer and healthier lives based on age and mortality rates, making it the perfect destination for the group of celebrities to transform their physical and mental wellbeing.
In 100 Years Younger in 21 Days, Gogglebox's Sandra Martin, Claire King (Coronation Street), musician Shaun Ryder, Sherrie Hewson (Benidorm), presenter Roy Walker, astrologer Russell Grant and Eastenders stars Sid Owen and June Brown will take part in an experiment to see if they can lose 100 years off their biological ages between them - without the aid of plastic surgery.
At the end of the grueling experiment, the group will be reassessed to see how many years they collectively shed off their biological ages and the changes to their health.
"Who doesn’t want to turn back the clock and look and feel a bit more youthful?" commented ITV's commissioning editor, Kate Teckman.
"Anti-aging concerns us all but to find out whether you can roll back the years by experiencing life in the Blue Zone, we have used leading experts and physicians along with a bunch of brave celebrities prepared to be put through their paces."
Executive producer Melissa Brown added: “We're thrilled to be working with ITV on this exciting new series, centred on the hot topic of anti-aging, 100 Years Younger in 21 Days promises laughter, shocking discoveries and some home truths."