In Brain Injury (working title), Theroux will spend time with staff and patients at the Brain Injury Rehabilitation Trust, one of the UK’s largest providers of neuro-behavioural rehabilitation, to find out how individuals and their loved ones cope with life-changing brain injuries that effect an estimated one million people in the UK.

The film will show how individuals with Acquired Brain Injury must cope with significant cognitive, behavioural and personality changes. While it is often called a ‘hidden disability’ because those affected can show little physical signs of change, sufferers must re-learn the basic skills of walking, talking and eating, as well as redeveloping complex personalities.

In Drinking to Oblivion, Theroux will immerse himself in the lives of patients at London’s King’s College Hospital who are struggling from alcohol addiction.

He will discover the many complex reasons that lead to the patients’ problems and why they find it so hard to stop drinking, even when it is killing them.

Speaking about the new commissions, Adam Barker, BBC Two Channel Editor, said he was “delighted” that Theroux was returning to the channel, and promised that he would cover the subjects “with his usual penetrating documentary gaze and commitment to unpicking complex human dilemmas with highly sophisticated filmmaking."