Amrita Acharia, Amanda Redman, and Neil Morrissey are the leading cast in ITV's upcoming six-part drama The Good Karma Hospital
The show is written by Death in Paradise's Dan Sefton with scripts from Vinay Patel and Nancy Harris and was cast in both the UK and Mumbai.
It tells the story of a cottage hospital that remains a pillar of the local community, despite being dreadfully under-funded and staffed by overworked medics.
Lead actor Acharia played handmaiden Irri in the hit fantasy drama Game of Thrones before being killed off in season 2.
Nepalese by birth, she will play British-Asian junior doctor Ruby Walker who travels to tropical South India to work in the eponymous run-down medical facility.
“It’s great to be cast in a Brit-Asian lead role in what’s an atypical coming-of-age story in many ways." Acharia said.
"The role of Ruby will be exciting to explore as she uproots the only home she knows, to be thrown into the deep end of a place with a different perspective on universal dilemmas of life, love, success and failure, and ultimately confronts herself with the past she was escaping from.”
New Tricks actress Amanda Redman will take on the role of the outlandish Dr Lydia Fonseca, the woman in charge of Good Karma Hospital.
She said: "I have always loved India and Sri Lanka. The people and varied cultures are fascinating, so spending time filming here couldn't be better. I also love the food, but will have to try and restrain myself. Easier said than done!”
Filming is due to begin on location in Sri Lanka later this month.